ea0041gp230 | Thyroid Cancer (1) | ECE2016
Marotta Vincenzo
, Sciammarella Concetta
, Capasso Mario
, Testori Alessandro
, Gambardella Claudio
, Grasso Marica
, Rubino Manila
, De Palma Maurizio
, Grazia Chiofalo Maria
, Pivonello Claudia
, Pivonello Rosario
, Santini Luigi
, Pezzullo Luciano
, Colao Annamaria
, Faggiano Antongiulio
Introduction: Constitution of new blood vessels is crucial for cancer self-maintenance and progression. Neo-angiogenesis may be affected from hereditary traits, namely the presence of SNPs (single nucleotide polymorphisms) of genes involved in its regulation. VEGF-A represents the main regulator of angiogenesis. Germline SNPs of the VEGF-A gene have been associated to outcome of several cancers, but no data exist about differentiated thyroid cancer (DTC).<p class="abstext"...