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Endocrine Abstracts

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ea0013p236 | Neuroendocrinology and behaviour (including pituitary) | SFEBES2007

PYY3–36 produces an acute anorexigenic effect followed by a later orexigenic effect not seen with other anorexigenic peptides

Parkinson James , Dhillo Waljit , Small Caroline , Ghatei Mohammed , Bloom Stephen

PYY is secreted postprandially from the endocrine L-cells of the gastrointestinal tract. PYY3–36, the major circulating form of PYY, reduces food intake in humans and rodents via high affinity binding to the auto-inhibitory NPY receptor, Y2R, within the hypothalamic arcuate nucleus.Aims: To investigate (1) the effects of length of fast on the anorexigenic actions of PYY3–36; (2) the effects of early light phase administrat...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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