Endocrine Abstracts

Objective: To investigate endocrine disorders concerning bone metabolism, thyroid and gonadal axis in treatment–naïve HIV-infected male patients.Subjects and methods: We studied 70 male, treatment-naïve patients (stage A=60, stage B=10) from the Infectious Diseases Unit of our Hospital. Anthropometric indices were measured and BMI was calculated for each participant. Blood samples were obtained after an overnight fasting for the evaluation...

Introduction: HIV infection has been associated with bone loss and increased frequency of bone fractures. The main pathogenetic mechanisms involve the direct effect of the virus and the HIV-induced inflammatory cytokines on bone metabolism, the effect of antiretroviral therapy (cART) per se and the frequently coexisting nutritional disorders and hypogonadism, further accelerating bone loss. Bisphosphonates remain the first-line treatment for these patients. Limited da...

Background: The incidence of endocrine complications among patients with HIV infection has decreased over the last years owing to widespread administration of combined Antiretroviral Therapy (cART) at early stages of the disease. We conducted a prospective observational study aiming to characterize the effects of cART on thyroid function in a cohort of newly diagnosed treatment-naive male patients.Materials and methods: Male subjects diagnosed with HIV i...