ea0006oc6 | Young Endocrinologist Session | SFE2003
Lovett F
, Gonzalez M
, Carter E
, Cobb L
, Salih D
, Tripathi G
, Holding C
, Pell J
The IGF-I receptor (IGF-IR) growth/survival pathways are engaged in crosstalk with pathways induced by cell-cell interactions. Different elements of the IGF-IR signalling system also affect the phosphorylation status of molecules involved in the regulation of cadherin-mediated cell-cell adhesion, such as catenins. In addition, the IGF-IR has been shown to co-precipitate with cell adhesion complexes.In this study, the crosstalk between IGF signalling and ...