ea0063gp235 | Anterior and Posterior Pituitary | ECE2019
Boertien Tessel
, Meijden Wisse van der
, Coumou Adriaan
, Drent Madeleine
, Someren Eus Van
, Romijn Hans
, Fliers Eric
, Bisschop Peter
Rationale: A history of optic chiasm compression in patients treated for sellar tumors is associated with alterations in sleep-wake rhythm. The optic chiasm contains axons of intrinsically photosensitive retinal ganglion cells (ipRGCs) that mediate photoentrainment of the suprachiasmatic nucleus. Compression could disrupt this entrainment leading to desynchronization with the 24-hour light-dark cycle. The post-illumination pupil response (PIPR) after blue light exposure is a u...