Endocrine Abstracts

Background: Bilateral total adrenalectomy (TA), despite causing persistent adrenal insufficiency with lifetime replacement of corticosteroids, is the method of choice in patients with bilateral pheochromocytoma. Partial adrenalectomy (PA) is an alternative approach that aims to balance tumor removal while maintaining adrenal function, although the oncological completeness of the procedure is questionable.Objective: The aim of this systematic review and m...

Background: Pheochromocytoma and paraganglioma (PPGL) are rare endocrine tumours that secrete catecholamines. Methoxycatecholamines in free plasma or fractionated methoxycatecholamines in 24-hour urine collections are the recommended tests for the diagnosis of pheochromocytoma, based on which patients are referred for surgical removal of the adrenal gland. However, false-positive results from these tests remain a problem and some patients are referred for adrenalectomy due to ...

Second malignant neoplasm following irradiation is a rare sequelae of primary childhood malignancies. Irradiation is a well-known risk factor for the development of benign and malignant thyroid tumors. Here we present the case of a young woman with medulloblastoma, who later developed thyroid cancer and eventually was also diagnosed with a cholangiocarcinoma.At the age of 7 the patient presented with headaches, nausea, vomiting, fatigue, somnolence and d...