ea0020p524 | Paediatric Endocrinology | ECE2009
Viazova Liudmila
, Solntseva Angelika
, Aksenova Elena
, Pokladok Tatiana
, Danilenko Nina
, Maitak Michail
Background and aims: High correlation is revealed between type 1 diabetes mellitus (DM1) and autoimmune thyroid pathology in children. Several candidate-genes including CTLA, PTPN, Ins-23Hphl could be associated with the combined autoimmune endocrinopathy. The aim of this study was to define whether polymorphisms of CTLA 49 A/G, PTPN22-1858 C/T, Ins-23Hphl ?/? genes contribute to DM1 and autoimmune thyroiditis (AT) combination development.Material and me...