Endocrine Abstracts

Amiodarone induced thyrotoxicosis (AIT) may develop in patients with either underlying thyroid disorders (type 1) or normal gland (type 2). The latter is considered a drug-induced destructive thyroditis, usually responding to glucocorticoids. Further treatments after restoring euthyroidism are often not necessary. The former is a true form of iodine-induced hyperthyroidism the management of which includes thionamides, potassium perchlorate and thyrodectomy. The prevalence of t...

Introduction: Autoantibodies against insulinoma-associated antigen-2 (anti-IA2) are an important marker for diagnosis and prediction of new-onset type 1 diabetes mellitus (T1DM). Here we report on a new prototype Anti-IA2 ELISA with shorter total incubation time (3h15min) compared to the established EUROIMMUN Anti-IA2 ELISA (minimum 17h40min). The study evaluates the performance of the prototype assay.Methods: The clinical performance of the prototype EL...