ea0032p15 | Adrenal cortex | ECE2013
Germano Antonina
, Rapa Ida
, Duregon Eleonora
, Votta Arianna
, Ardito Arianna
, Volante Marco
, Papotti Mauro
, Terzolo Massimo
Objective: In vitro data suggest that somatostatin receptors (SSTR) and mTOR pathways might represent reasonable targets for novel therapies, since are involved in growth of adrenocortical carcinoma (ACC). However, in vitro analysis of combination treatments, targeting both mTOR and SSTR as compared to mitotane, and detailed tissue typing mTOR/SSTR pathway are poorly explored in ACC.Methods: This study was designed to characterize the t...