Endocrine Abstracts

Chronic obstructive pulmonary disease (COPD) patients could have altered endocrine function as different endocrine organs (gonads, pituitary, thyroid and pancreas) can be affected depending on the phenotype of the disease and the degree of systemic inflammation. Anabolic hormones can be involved as COPD patients can show weight loss and muscle wasting and both these conditions can modify natural history of the disease. Moreover COPD patients can frequently have acute exacerbat...

Previously, we demonstrated an inverse correlation between CoenzymeQ10 (CoQ10) and thyroid hormones, suggesting its usefulness as index of thyroid hormone tissue effect. A low-T3 syndrome, observed in chronic diseases, is considered an adaptive mechanism and its treatment is still debated. To evaluate the metabolic status of these patients and antioxidant vs energetic role of CoQ10, we studied 32 patients, with chronic obstructive pulmonary disease (COPD), comparing respirator...