ea0067o40 | Oral Presentations | EYES2019
Coopmans Eva C
, Schneiders Joppe J
, El-Sayed Nour
, Erler Nicole S
, Hofland Leo J
, Petrossians Patrick
, van den Berg Sjoerd
, van der Lely Aart-Jan
, Muhammad Ammar
, Neggers Sebastian JCMM
Objective: MRI T2-signal intensity and somatostatin (SST) receptor expression are recognized predictors of therapy response in acromegaly. We investigate the relationship between these predictors and the hormonal and tumor responses to PAS-LAR therapy, and compare to first-generation somatostatin receptor ligands (SRLs) responsiveness.Methods: We included 45 acromegalics initially receiving SRLs, followed by a combination therapy including pegvisomant (P...