ea0089b15 | Basic Science | NANETS2022
Scotto PhD Luigi
, Safari PhD Maryam
, Hou Ping
, Fojo, MD PhD Tito
, Bates MD Susan
Background: More than 12,000 people in the United States are diagnosed with a NET each year and approximately 175,000 people are living with this diagnosis. Little progress has been made in the therapy of NETs over the last two decades, and identification of new vulnerabilities remains a priority.Methods: We used two libraries of compounds selected for potential repurposing and identified agents with the highest cytotoxic activity in neuroendocrine model...