ea0029p341.1 | Cardiovascular Endocrinology and Lipid Metabolism | ICEECE2012
Nguyen J P
, Frost C D
, Lane M L
, Skelton W P
, Skelton M
, Vesely D L
Introduction: The growth of human tumors depends on the formation of new blood vessels and vascular endothelial growth factor (VEGF) helps control this process via inducing new capillaries to sprout from pre-existing blood vessels. Four cardiac hormones which eliminate up to 80% of human pancreatic cancers and up to 86% of human small-cell lung cancers growing in mice were investigated for their effects on VEGF and the VEGFR2/KDR/Flk-1 receptor. The VEGFR2 receptor is the main...