ea0081p267 | Adrenal and Cardiovascular Endocrinology | ECE2022
Nakhleh Afif
, Saiegh Leonard
, Supino-Rosin Lia
, Gendelman Raya
, Shehadeh Naim
, Zloczower Moshe
Introduction: The 250 μg cosyntropin stimulation test (CST) is used to diagnose non-classic congenital adrenal hyperplasia (NCCAH). The current recommendation to perform CST is when follicular morning 17-hydroxyprogesterone (17OHP) is higher than 6 nmol/l, and CST is considered positive for NCCAH diagnosis when the 60-minutes post-CST 17OHP serum level is above 30 nmol/l. These cut offs are mainly derived from radioimmunoassay (RIA) data. Recently, a validated enzyme-link...