ea0029p850 | Endocrine tumours and neoplasia | ICEECE2012
Furnica R.
, Gigot J.
, Deprez P.
, Buysschaert M.
, Maiter D.
Background: Patients with an insulinoma are at variable risk of severe hypoglycemia due to wide ranges of both tumoral insulin secretion and peripheral tissue sensitivity to chronic hyperinsulinaemia.Objectives: In this study we investigated the clinical, biological and tumoral characteristics of a large series of patients with immunohistochemically confirmed insulinoma and we assessed both insulin sensitivity and beta-cell function in fasting steady-sta...