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ea0098c51 | Clinical – Surgery/Applied Pathology | NANETS2023

A prospective phase ii single-arm trial on neoadjuvant peptide receptor radionuclide therapy (PRRT) with 177Lu-DOTATATE followed by surgery for pancreatic neuroendocrine tumors (NeoLuPaNET)

Partelli Stefano , Landoni Luca , Bartolomei Mirco , Zerbi Alessandro , Maria Grana Chiara , Boggi Ugo , Butturini Giovanni , Casadei Riccardo , Bassi Claudio , Falconi Massimo

Background: Surgical resection of Nonfunctioning Pancreatic Neuroendocrine Tumor (NF-PanNET) is curative in most of the cases. Neoadjuvant treatments in patients with resectable NF-PanNET at high-risk of recurrence have never been investigated. Aim of this study was to test the safety and efficacy of neoadjuvant PRRT with 177Lu-DOTATATE followed by surgery in patients with resectable high-risk NF-PanNET.Methods: This was a multi-center single-...

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Endocrine Abstracts

A prospective phase ii single-arm trial on neoadjuvant peptide receptor radionuclide therapy (PRRT) with 177Lu-DOTATATE followed by surgery for pancreatic neuroendocrine tumors (NeoLuPaNET)

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