Endocrine Abstracts

Background: Adipose tissue blood flow (ATBF) is important for delivering nutrients and oxygen to adipose tissue (AT), and distributing adipokines and metabolites into the circulation. ATBF has been measured with the 133Xenon wash-out technique (gold standard), microdialysis, laser Doppler Fluximetry, and contrast-enhanced ultrasound. However, due to decline in world-wide 133Xenon production and the invasive nature of other techniques, an alternative metho...

Background: Abdominal obesity is associated with insulin resistance and increased cardiometabolic disease risk, whereas lower-body fat accumulation seems protective against metabolic derangements. Differences in upper-body and lower-body adipose tissue (AT) function seem to underlie these opposing associations. Here, we investigated the inflammatory signature of upper- and lower-body AT in women with normal weight and obesity, as well as in human primary abdominal (ABD) and fe...