Endocrine Abstracts

Objective: Our aim was to evaluate whether multiple mild head trauma or repetitive heading of long term soccer playing causes growth hormone deficiency.Patients and methods: 28 retired previously professional male soccer players were investigated. Nine of them had sport related head injuries. Mean age: 48.7 years (range 36–70; S.D.±7.4); mean sport duration (professional and senior activity): 27.4 years (S.D.±...

Background: The detectable levels of thyroid antibodies in patients suffering from Riedel’s chronic fibrosing thyroiditis (RT) suggest a link between RT and Hashimoto’s thyroiditis, but the pathogenesis of RT is not really known. Lyme disease is the most frequent tick-borne infection with variable manifestations in different organs caused by Borrelia burgdorferi (Bb).Case report: A 59-year-old woman presented in our outpatient clinic wit...

Objective: To identify MetS and non-MetS in subjects with adult-onset GHD before start of GH replacement and to compare prevalence of cardiovascular risk factors.Subjects and methods: MetS was defined (IDF criteria) by the obligatory presence of increased waist circumference (WC) and presence of at least two of following components: hypertension, decreased HDL-cholesterol, increased triglycerides, diabetes mellitus. The complementary group was defined as...

Background: Untreated GH-deficiency (GHD) in adults has been suggested to be associated with an increased prevalence of type 2 diabetes mellitus (DM). Proposed causative factors are the tendency to overweight and the insulin resistance due to central adiposity.Patients and methods: The KIMS (Pfizer International Metabolic Database) was used to evaluate the prevalence of DM in both childhood-onset (CO; n=1977; 56% males) and in adult-onset (AO; ...

Introduction: Real-world data on management of bone alterations in Cushing’s syndrome (CS) are scanty. The aim of our study was to assess the prevalence of osteoporosis (OP) and bone fractures (BF) in CS patients included in the European Registry on Cushing’s Syndrome (ERCUSYN), and to describe the diagnostic and therapeutic strategies adopted across Europe to address these comorbidities.Patients and methods: In this retrospective, observationa...