Endocrine Abstracts

Introduction: Acne vulgaris is a common skin disorder among both adolescents and adults. Its multifactorial pathogenesis may include insulin resistance, especially in cases resistant to classical treatment methods. There are few studies which have already proved acne vulgaris development in the course of insulin resistance, however, there are more studies necessary in order to include insulin resistance evaluation in classical acne vulgaris diagnosing and treatment.<p clas...

Introduction: The CHEK2 gene is involved in DNA repair. Germline mutations in the CHEK2 gene impair this mechanism, increasing the risk of various cancers, including papillary thyroid cancer (PTC). There are four different mutation variants in the CHEK2 gene in the Polish population: three truncating mutations (1100delC, IVS2+1G>A and del53950) and one missense mutation (I157T).Material: The study included 1,547 PTC patient...