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ea0099rc10.1 | Rapid Communications 10: Calcium and Bone | Part II | ECE2024

First-line F18-choline PET/CT Versus Tc99m-sestaMIBI SPECT/CT in the surgical management of primary hyperparathyroidism: a diagnostic randomized phase III trial

Quak Elske , Lasne-Cardon Audrey , Cavarec Marie-Beatrice , Lireux Barbara , Bastit Vianney , Roudaut Nathalie , Salaun Pierre-Yves , Keromnes Nathalie , Potard Gael , Vaduva Patricia , Esvant Annabelle , Jegoux Franck , De Crouy-Chanel Olivier , Devillers Anne , Guery Clemence , Christy Francois , Grellard Jean-Michel , Bardet Stephane , Clarisse Benedicte

Introduction: Whether F18-choline PET/CT (FCH PET/CT) should replace Tc99m-sestaMIBI SPECT/CT (MIBI SPECT/CT) as a first-line imaging technique for preoperative localisation of parathyroid adenomas in primary hyperparathyroidism (pHPT) is unclear.Methods: We conducted a multicentre randomized open diagnostic intervention phase III trial in adults with primary hyperparathyroidism and indication for surgical treatment. Patients were assigned in a 1:1 ratio...

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First-line F18-choline PET/CT Versus Tc99m-sestaMIBI SPECT/CT in the surgical management of primary hyperparathyroidism: a diagnostic randomized phase III trial

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