Endocrine Abstracts

Purpose: For vaginoplasty of Rokitansky syndrome, we use oxidized regenerated cellulose instead of bio-craft that has been used in the past because it requires a less invasive and more physiological surgery. However, the mechanism of epithelialization of this procedure is still not clear. There is a report that differentiation and proliferation of the vaginal epithelium of newborn mice is promoted by administration of basic fibroblast growth factor (bFGF).<p class="abstext...

Purpose: Disorders of sex development (DSD) are defined as having, ‘A chromosome, germinal gland, or anatomical structure that is atypical in the native state’. There are two types of patients with DSD who consult a gynecologist: patients diagnosed in childhood (group A), and patients diagnosed based on unusual secondary sex characteristics in adolescence (group B). In group A, gynecologists are required as a member of a multidisciplinary medical team for DSD. On the...

Introduction: Since primary amenorrhea because of ovarian dysfunction is a common complication in women with Turner syndrome (TS), sex hormone replacement therapy (HRT) is mandatory for induction of puberty, such as acquisition of secondary sexual characteristics and increased bone density. However, appropriate treatment protocols have not yet been established. To evaluate the efficacy of HRT on puberty induction in our department, a retrospective analysis was conducted.<p...