ea0049ep506 | Diabetes complications | ECE2017
Kim Hye-Soon
, Bae Kwi Hyun
, Jung Gwon Soo
, Ham Hye Jin
, Park Bo Yoon
, Choi Yeon Kyung
, Seo hyun Ae
, Seo Jung Beom
, Park Keun Gyu
Renal tubulointerstitial fibrosis is a common feature of the final stage of nearly all cause types of chronic kidney disease. Although classic peroxisome proliferator-activated receptor-gamma (PPARĪ³) agonists have a protective effect on diabetic nephropathy, much less is known about their direct effects in renal fibrosis. This study aimed to investigate possible beneficial effects of lobeglitazone, a novel PPARĪ³ agonist, on renal fibrosis in mice with unilateral uret...