ea0031oc3.8 | Reproduction, growth and development | SFEBES2013
Hand Laura
, Ray David
, Loudon Andrew
, Bechtold David
, Cooper Garth
Adiponectin, an exclusive adipose-derived hormone, circulates at high concentration, and exerts metabolic effects. Adiponectin levels in the circulation correlate negatively with BMI, and low adiponectin concentrations are associated with the low grade inflammation and metabolic dysfunction that accompanies obesity. Adiponectin has been reported to have potent anti-inflammatory activities, and to exert these effects by regulating macrophage function. The mechanism of adiponect...