ea0016p595 | Paediatric endocrinology | ECE2008
Deutschbein Timo
, Unger Nicole
, Hauffa Berthold
, Mann Klaus
, Petersenn Stephan
Introduction: Optimizing glucocorticoid (GC) therapy in patients with congenital adrenal hyperplasia (CAH) remains a challenge. While overdosing may result in Cushings syndrome, underdosing is associated with female virilization and adrenal insufficiency. This study evaluated day-profiling of salivary 17-hydroxyprogesterone (17OHP) for the biochemical control of adolescents with CAH due to 21-hydroxylase deficiency.Methods: Twelve patients (4 males...