Searchable abstracts of presentations at key conferences in endocrinology

ea0099p500 | Endocrine-Related Cancer | ECE2024

Catching the silent culprits: Prospective TERT promoter mutation screening for minimally invasive follicular and oncocytic thyroid carcinoma in clinical practice

Hellgren L Samuel , Stenman Adam , Larsson Catharina , Zedenius Jan , Juhlin C Christofer

De-escalation of thyroid cancer treatment is crucial to prevent over-treatment of indolent disease. However, it also underscores the importance of identifying potential clinically aggressive cases that require completion lobectomy and adjuvant radioiodine therapy. TERT promoter mutations are molecular events closely associated to high-risk thyroid tumors with poor outcome, and may serve as markers for cases at risk of dissemination. In various international guidelines...