ea0034p263 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2014
Ramanjaneya Manjunath
, Tan Bee
, Patel Vanlata
, Hu Jiamiao
, Lehnert Hendrik
, Hillhouse Edward
, Chen Jing
, Randeva Harpal
Renalase is a recently discovered flavin adenine dinucleotide (FAD)-dependent oxidase, predominantly secreted into the circulation from the kidney and regulates catecholamine degradation and metabolism. Renalase gene is also present in heart muscle, skeletal muscle and liver cells in humans, and in mouse testicles. Four isoforms of renalase gene has been identified in humans (hRenalase1 to hRenalase4), however only hRenalase1 is detected in human blood suggesting that hRenalas...