ea0020p498 | Obesity and Metabolism | ECE2009
Yoo Soon Jib
, Hong Oak Kee
, Kim Do Man
, Kwon Hyuk Sang
, Son Ho Young
, Kang Sung Koo
, Kim Dong-Sun
Aims: To investigate the mechanism of α-lipoic acid (ALA) on preventing diabetes, we evaluated the effect of ALA on growth regulation and composition of skeletal muscle.Methods: OLETF and LETO rats, aged 24 weeks, were treated with or without ALA (100 mg/kg body weight/day in drinking water) and / or insulin (insulin glargine, 2 U/kg body weight/day; subcutaneous injection) for 8 weeks.Results: The treatment of ALA with or wit...