Abstract Search

ea0020p518 | Paediatric Endocrinology | ECE2009

A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys

Juul Anders , Sorensen Kaspar , Aksglaede Lise , Garn Inger , Rajpert-deMetys Ewa , Hullstein Ingunn , Hemmersbach Peter , Ottesen Anne-Marie

Testosterone (T) is excreted in urine as water soluble glucuronidated and sulphatated conjugates. The ability to glucuronidate T and other steroids depends on a number of different glucuronidases (UGT) of which UGT2B17 is essential. The aim of the study was to evaluate the influence of UGT2B17 genotypes on urinary excretion of androgen metabolites in pubertal boys.Study design: A clinical study of 116 healthy boys aged 8 to 19 years. UGT2B17</i...

0 shares

Endocrine Abstracts

A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys

BiosciAbstracts