ea0029oc5.1 | Obesity Basic | ICEECE2012
Okamoto Y
, Fukushima M
, Ishii S
, Okamoto M
, Katsumata H
, Minami S
Objectives: Secretion of GH, a pituitary and anabolic hormone that reduces visceral fat, is diminished in obese or elderly subjects. The reduced GH may induce visceral fat accumulation and subsequently accelerate metabolic syndrome in these population. In the present study, we sought the effect of chronic GH supplement on visceral fat and glucose metabolism in diet-induced obese (DIO) mice.Methods and results: Male obese mice (C57BL/6, 12 weeks old) unde...