Endocrine Abstracts

Introduction: During pregnancy (state with physiological hyperprolactinemia-HP) mothers require larger calcium amount for fetal growth. It has been shown that PRL stimulate intestinal calcium absorption in physiological HP, which can protect mother’s skeletal system from further mineral density loss. On the other hand, medicamentous-related hyperprolactinemia is more frequently associated with reduced BMD and increased fracture risk. We conducted the experimental study to...

Introduction: The aim of this study was to evaluate potential alterations in prolactin receptor gene expression (Prlr) in the duodenum, vertebra, and kidney - key organs in calcium metabolism, across the aging process.Methods: Wistar female rats were divided into: Group A (10 rats, 5 weeks old), Group B (10 rats, 18 weeks old) and Group C (7 rats, 21 weeks old). Laboratory analysis included: prolactin, serum ionized calcium, phosphorus, urinary ...