ea0084ps2-06-53 | Hypothyroidism Treatment | ETA2022
R. Riis Kamilla
, B. Larsen Camilla
, R. Medici Bjarke
, Jensen Christian Z.
, H. Winter Kristian
, L. Larsen Emil
, Bronden Andreas
, Ellervik Christina
, L. la Cour Jeppe
, Hegedus Laszlo
, H. Brix Thomas
, E. Poulsen Henrik
, Faber Jens
, K. Knop Filip
, Nygaard Birte
, J. Bonnema Steen
Introduction: Hypothyroidism has been associated with oxidative stress. Urinary excretion of 8-oxo-7,8-dihydroguanosine (8-oxoGuo) and 8-oxo-7,8-dihydro-2-deoxyguanosine (8-oxodG), respectively, represent whole-body RNA and DNA oxidation. While these biomarkers have been associated with increased morbidity and mortality in various diseases, they have been only sparsely explored in patients with thyroid disorders.Method: In 45 women with newly diagn...