Endocrine Abstracts

Primary hyperaldosteronism is a common cause of secondary hypertension. Distinguishing between the two subtypes (unilateral aldosterone-producing adenoma and bilateral idiopathic hyperaldosteronism) is crucial for patient’s management. Adrenal venous sampling is an important method for evaluation of the condition, but selective successful right adrenal venous sampling is often reported to be a difficult procedure. A retrospective review of 51 cases suffering from primary ...

Introduction: Acromegaly is a chronic disease characterized by prognatism, frontal bossing, coarsened facial features, enlarged hands and feet due to overproduction of growth hormone (GH) generally by a pituitary adenoma. Here, we aimed to present an acromegalic patient presented with retropharyngeal hypertrophy first time in the literature.Case report: 65-year-old female patient had been referred to our department from otorhinolaryngology outpatient-cli...

Introduction: Amyloidosis is characterised by accumulation of amorph and proteinous substance in several tissues and organs. Thyroid, adrenal, and pituitary insufficiencies may rarely be observed due to accumulation of these substances. Here, we present a case to point out this rare condition.Case report: A 19-year-old male patient admitted with complaints of swelling in the neck, abnormality in thyroid hormone levels and fatigue. He had been diagnosed w...

Introduction: Acromegaly is chronic debilitating disease related with excess GH and insülin-like growth factor 1 (IGF1) secretion. Pegvisomant is a GH receptor antagonist that competes with endogenous GH for its receptor and is often used as a medical therapy in patients with inadequate response to somatostatin analogs.Methods: Forty-six patients are followed with the diagnosis of acromegaly in our clinic. We present the results of six acromegalic p...

Objective: Migraine is a common primary headache disorder that affects 12-15% of the general population. Also, vitamin D deficiency is a global health problem. A few studies have shown relationship between serum vitamin D levels and headache. The aim of this study was to investigate the difference in serum levels of 25-Hdroxy vitamin d [25(OH)D] between migraine patients and healthy controls and also to determine the relationship of vitamin D deficiency with frequency and seve...

GAPO syndrome (OMIM 230740) is a rare, multiple congenital anomalies syndrome characterized by Growth retardation, Alopecia, Pseudoanodontia and Ocular manifestations. Syndrome caused by anthrax toxin receptor 1 (ANTXR1) gene (NM_032208.2) mutation leading to deficiency of an enzyme involved in the metabolism and breakdown of extracellular matrix (ECM). Disease show parental consanguinity, autosomal recessive inheritance and since first description in 1947 a total of 38 patien...

Aim: Obstructive sleep apnea syndrome (OSAS) has been studied rarely in patients with Cushing’s syndrome. We investigated the possible association between Cushıng’s syndrome and OSAS in this study.Method: Thirty female patients with newly diagnosed Cushing’s syndrome and 30 female obese control subjects were included in this study. All the participants were evaluated by polysomnography. OSAS was defined as apneahypopnea index (AHI) of...

Introduction: Many endocrinopathies such as acromegaly, Cushing’s syndrome (CS), pheomochromocytom and lipodystrophia can be associated with insülin resistance and unregulated diabetes mellitus (DM).Case report: A 37 –year- and 2 months pregnant women admitted to our out patient clinic for regulation of hyperglycemia. On physical examination; Blood Pressure: 140/95 mmHg, Body Mass Index: 31 kg/m2, central obesity, acanthosis nig...

Introduction: Warthin-like papillary thyroid carcinoma (WLPTC) is a rare variant of thyroid papillary carsinoma (TPC). We present these cases to point out this rare variant.Case reports: Case 1: A 38-year-old woman admitted to outpatient clinic with a thyroid nodule. Ultrasonography of thyroid gland revealed bilateral multinodular goiter with microcalcifications. Thyroid autoantibodies were elevated. Thyroid function tests (TFT) were normal. Fine-needle ...

Introduction: Despite having different embriogenic origins, thyroid medullary carcinoma and follicular carcinoma may be seen together as mixed medullary-follicular thyroid carcinoma. We present a rare case of mixed medullary-follicular cell carcinoma of thyroid which has a progressive and aggressive nature.Case report: A 68-year-old female patient admitted with complaint of a lump in her neck. Ultrasonography of thyroid gland revealed a 37×35 mm sol...