ea0011p398 | Diabetes, metabolism and cardiovascular | ECE2006
McGee KC
, da Silva NF
, Baker AR
, Harte AL
, Creely SJ
, Hill MJ
, Khanolkar M
, Evans M
, Kumar S
, McTernan PG
Visfatin, a novel adipocytokine preferentially expressed in omental (Om) adipose tissue (AT), has been shown to exert insulin-mimetic effects in mice and humans. Recent studies in Asian populations show elevated serum visfatin levels in subjects with Type 2 Diabetes Mellitus (T2DM), suggesting a potential role for visfatin in the pathogenesis of this disease. Whilst central adiposity is closely related to IR and T2DM, the role of AT in the development of these conditions remai...