ea0007oc6 | Reproduction | BES2004
Kirkup S
, Cheng Z
, Chin E
, Elmes M
, Wathes D
, Abayasekara D
Cervical dilatation and myometrial contractions are essential processes of both pre-term and term labour. These processes are associated with enhanced production of 2-series prostaglandins (PGs) from polyunsaturated fatty acids (PUFAs), by feto-placental tissues. Some human epidemiological studies suggest that specific PUFAs can alter the length of gestation. The amnion is a prime site for PG synthesis in the feto-placental unit. Thus perturbations of PG synthesis in this tiss...