ea0035p117 | Calcium and Vitamin D metabolism | ECE2014
Somjen Dalia
, Kulesza Urszula
, Sharon Orli
, Knoll Esther
, Stern Naftali
Vitamin D receptors (VDRs) are expressed in bone and vascular cells which also respond to vitamin D treatment by modulation of cell proliferation measured by DNA synthesis and energy metabolism measured by CK specific activity. We have previously observed that vitamin D-related compounds target several genes which affect cell proliferation, including mRNA expression of estrogen receptor (ER)α, ERβ, VDR, 1α hydroxylase of 25OHD3 (1OHase) and 12 and 15 lipoxygenas...