ea0014p224 | (1) | ECE2007
Park Joong-Yeol
, Won Jong Chul
, Lee Ki-Up
, Lee Woo Je
, Ko Kyung Soo
, Song Kee-Ho
, Lee In-Kyu
Aims: Central obesity is associated with increased cardiovascular morbidity and mortality. It has been proposed that increased lipid accumulation in vascular tissue and the consequent increase in oxidative stress may be a missing link between obesity and atherosclerosis. The peroxisome proliferators-activated receptor (PPAR)-γ coactivator 1-α (PGC-1α) is a transcriptional coactivator playing an important role in energy metabolism. PGC-1α is present in vascu...