Searchable abstracts of presentations at key conferences in endocrinology

ea0099p429 | Adrenal and Cardiovascular Endocrinology | ECE2024

Establishing cut-off values for late-night salivary cortisol and cortisone measured by LC–MS/MS in the diagnosis of endogenous hypercortisolism

Koops Karlijn , Bisschop Peter H , Heijboer Annemieke C , Hillebrand Jacquelien

Background: Diagnosing endogenous Cushing’s syndrome (CS) is often challenging because of the difficulty in interpreting results of dynamic endocrine tests. One of the recommended initial tests is the measurement of late-night salivary cortisol (LNSaCl). Some articles describe added value of late-night salivary cortisone (LNSaCn) measurements. However, published cut-off values of LNSaCl and LNSaCn vary widely between studies, which may be related to different experimental...