ea0098b26 | Basic Science | NANETS2023
David Seo MD Y.
, Witt MD, MAS Russell G.
, Lazcano MD Rossana
, MD Samuel Cass
, Hudgens Courtney
, Wani Khalida
, Chelvanambi PhD Manoj
, Johnson MS Sarah
, Hernandez MD Sharia D.
, Halperin MD Daniel M.
, Lazar MD, PhD Alexander J.
, Wargo MD, MMSc Jennifer A.
, Estrella MD Jeannelyn S.
, Maxwell MD, MBA Jessica E.
Background: Patients with small bowel neuroendocrine tumors (SBNETs) frequently present with metastatic disease, and unfortunately, the range and efficacy of available therapies is limited. Immunotherapeutic checkpoint inhibitors have demonstrated benefit in other malignancies and may also play a role in SBNETs, although relatively little is known about the immune infiltrate in these tumors. Toward a goal of developing novel immunomodulatory strategies, we sought to evaluate t...