ea0073pep12.6 | Presented ePosters 12: Diabetes, Obesity, Metabolism and Nutrition | ECE2021
Daffara Tommaso
, Mancioppi Valentina
, Caputo Marina
, Leone Ilaria
, Ferrero Alice
, Pelosini Caterina
, Santini Ferruccio
, Aimaretti Gianluca
, Ceccarini Giovanni
, Prodam Flavia
BackgroundIn lipodystrophy (LD) adipose tissue function is impaired, leading to a severe metabolic syndrome. Familiar Partial LD (FPLD) type I (Kobberling Syndrome) overlaps with Cushings syndrome phenotype. The latter and the metabolic impairment observed in FPLD1 may suggest a crosstalk between the HPA axis, assuming that leptin sensitivity is preserved in this context. We aimed to evaluate if leptin levels are associated with glucocorticoid acti...