ea0036P20 | (1) | BSPED2014
Giri Dinesh
, Das Urmi
, Blair Jo
, Didi Mo
, Hayden James
, Brook Lynda
, Selby Peter
, Senniappan Senthil
, Dharmaraj Poonam
Introduction: Hypercalcaemia secondary to malignancy is rare in children. PTH-rP secreted by malignant cells increases bone resorption and renal calcium retention causing hypercalcaemia. We report a case of hypercalcaemia refractory to bisphosphonate and corticosteroid therapy, but responsive to treatment with Denosumab.Case report: A 17-year-old boy with epidermolysis bullosa presented with advanced squamous cell carcinoma of the left leg and symptomati...