Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep558 | Endocrine-Related Cancer | ECE2024

99mTechnetium-labeled GRPR antagonist for the imaging of prostate cancer – first clinical images

Bromińska Barbara , A. Nock Berthold , Maina Theodosia , Kaloudi Aikaterini , Kanellopoulos Panagiotis , Janota Barbara , Mikołajczak Renata , Ruchała Marek , Czepczyński Rafał

Introduction: Nuclear medicine procedures offer a possibility of tracing tumor cells based on their physiology. Gastrin-Releasing Peptide receptor (GRPr) is aberrantly expressed in numerous cancers, among them prostate cancer. Demobesin-15 ([99mTc]DB15) is a novel GRPR-antagonist designed for the evaluation of GRPr expression in different tumors. It has been shown to accumulate in animal prostate cancer models. Hereby, we present our experiences with the first in-hu...