ea0027p75 | (1) | BSPED2011
Sun A P C
, Kirby B
, Helms P J
, Black C
, Simpson C R
, McLay J S
Introduction: Most paediatric medicines have not undergone extensive clinical trials in children and as a necessity are frequently prescribed off-label, a practice which is recognised to be associated with an increased risk of adverse drug reactions (ADRs).Aims: To assess the use of routinely acquired healthcare data to identify medication utilisation and specifically drug discontinuation, as a signal for possible ADR occurrence in children: using orlist...