Endocrine Abstracts

Background: Recent data suggest a direct impact of ghrelin and leptin on the immune system. Ghrelin appears to antagonize these effects. The role of ghrelin and leptin in the context of ANCA-associated vasculitis (AV) has not been reported.Methods: Fasting serum ghrelin, free and bound leptin levels were measured in 44 patients with active AV and 25 in matched healthy controls. Follow-up under immunosuppressive therapy was available in 25 patients (1, 3,...