ea0015p352 | Thyroid | SFEBES2008
Correia Neuman
, Mullaly Sinead
, Cooke Gillian
, Tun Tommy Kyaw
, Phelan Niamh
, Feeney Joanne
, Fitzgibbon Maria
, O'Mara Shane
, Boran Gerard
, Gibney James
Memory formation largely depends on normal function of the temporal lobes (particularly the hippocampal complex) and prefrontal cortex. Evidence from animal studies suggests abnormal hippocampal function in hypothyroidism1. We hypothesized that specific defects in hippocampal-dependent memory would be observed in hypothyroid patients. Patients with overt (n=17) and subclinical (n=17) hypothyroidism underwent neuropsychological testing at baseline, 3 an...