Endocrine Abstracts

Gestational diabetes mellitus (GDM) is a clinical condition which is ideal for evaluating short-term effects of impaired glucose metabolism, ruling out the possibility that the platelet abnormalities are a consequence of diabetic complications.The aim of this study was to measure the velocity of platelet disaggregation and the activation of the platelet second messengers cGMP and cAMP by sodium nitroprusside (SNP) and ATP, respectively, in vitro i...

Background: The prevalence of type 1 diabetes mellitus (DM) among patients with primary adrenal insufficiency (Addison’s disease) is 3-4 times higher than the expected prevalence in the population. The mortality rate due to DM is more than 3-fold the mortality rate in the background population. The impact of DM on mortality rate in patients with Addison’s disease is not known.Objectives: To study the frequency of DM and its impact on mortality ...