ea0073oc8.6 | Oral Communications 8: Pituitary and Neuroendocrinology | ECE2021
Ringvoll Normann Kjersti
, Kristin Berland Astrid Berland
, Olsen Linn Guro
, Lekva Tove
, Dahlberg Daniel
, Bollerslev Jens
, Petter Berg Jens
, Cristina Olarescu Nicoleta
BackgroundCorticotroph pituitary adenomas present different degrees of functionality, from silent to whispering and finally to functioning adenomas leading to Cushings disease. Compared to their functioning (FCA) counterpart, the silent corticotroph adenomas (SCA) express lower levels of the corticotroph cell lineage marker–TBX19 (TPIT), proopiomelanocortin (POMC), and prohormone converting enzyme 1/3 (PC1/3, PCSK1)–t...