ea0022p375 | Endocrine Disruptors | ECE2010
Farholt Stense
, Sode-Carlsen Rasmus
, Christiansen Jens Sandahl
, Ostergaard John Rosendahl
, Hoybye Charlotte
Objective: PWS is associated with hypogonadism and partial GH insufficiency. In addition partial insufficiency of the hypothalamicpituitaryadrenal (HPA) axis recently was suggested (de Lind van Wijngaarden 2008) based upon an insufficient response to an overnight single-dose metyrapone in 15 out of 25 (60%) children. We aimed at further exploring this potentially dangerous condition.Methods: During a 1-year period genetically verified PWS pat...