Endocrine Abstracts

Adrenal insufficiency, characterised by inadequate cortisol production, significantly impacts quality of life and overall health. Current treatment primarily involves hydrocortisone replacement. However, dosing challenges and risk of adverse cardiovascular complications persist with this therapy. Consequently, there is a pressing need for safer glucocorticoid replacement options to mitigate the cardiometabolic toxicity, while effectively managing adrenal insufficiency. Prelimi...