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Endocrine Abstracts

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ea0037ep590 | Obesity and cardiovascular endocrinology | ECE2015

Genetic variation in GLP1 receptor is associated with interindividual differences in weight lowering potential of liraglutide in obese women with PCOS

Jensterle Mojca , Pirs Bostjan , Goricar Katja , Dolzan Vita , Janez Andrej

Objective: The weight lowering potential of glucagon-like peptide (GLP) 1 receptor agonists (RAs) is interindividually different and clinically unpredictable. The potential role of genetic variability of GLP1R on body weight response to GLP1 RA has not yet been evaluated. The aim of the study was to assess the effect of common non-synonymous GLP1R single nucleotide polymorphisms (SNPs) rs6923761 and rs10305420 on weight loss in response to long acting GLP1 RA liraglut...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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