ea0029p1268 | Obesity | ICEECE2012
Pizza G.
, Di Somma C.
, Orio F.
, Valentino R.
, Nedi V.
, Brancato V.
, Lombardi G.
, Colao A.
, Savastano S.
Introduction: Several cross-sectional studies evidence the association between hypovitaminosis D, obesity, insulin resistance (IR), and polycystic ovary syndrome (PCOS) cohorts, although the role of obesity per se is still debatable. Increased leptin-to-adiponectin ratio (L/A) and low-grade chronic inflammation markers, both due to accumulation of dysfunctional adipocytes, have been recently reported in PCOS. Aim of our study was to investigate the relative roles of obe...